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Fig. 8 | BMC Cancer

Fig. 8

From: Desmoglein 2 and desmocollin 2 depletions promote malignancy through distinct mechanisms in triple-negative and luminal breast cancer

Fig. 8

XAV-939 abolished shDsg2- and shDsc2- induced proliferation and migration in MCF-7 cells. (A) Plate clone-forming assays showed β-catenin inhibitor XAV-939 (5µM) could attenuate capacity of proliferation in shDsg2 and shDsc2 MCF-7 cells. (B) Wound-healing assay displayed XAV-939 (5µM) abrogated shDsg2- and shDsc2- induced migration in MCF-7 cells. The scale bar represents 100 μm. Data are presented as mean ± SD from three separate experiments. *indicates P < 0.05; ns, not significant

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BMC Cancer

ISSN: 1471-2407

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